Human IL-1 Alpha/IL-1F1/IL1A ELISA Kit PicoKine®
ELISA Kit supplied by Boster Bio Read more ›
Product Description
Interleukin-1 alpha (IL-1 alpha) and interleukin-1 beta (IL-1 beta) are two biochemically distinct, but distantly related, polypeptidic cytokines that play a key role in inflammation, immunologic reactions, and tissue repair. IL-1 alpha has been implicated in the pathogenesis of infectious, autoimmune and inflammatory diseases. Recently, it has been shown that IL-1 alpha is identical to hematopoietin 1, which is described as a hematopoietic growth factor acting on early progenitor cells in synergy with other hematopoietic growth factors. The human interleukin 1 alpha gene is assigned to chromosome 2. Genetic polymorphisms at interleukin (IL)-1alpha and IL-1beta have been recently suggested to be associated with severity of adult periodontitis. The murine IL-1 alpha and IL-1 beta genes encode structurally and evolutionarily related cytokines that exert a regulatory role in numerous physiological processes including hemopoiesis. The standard product used in this kit is recombinant human IL-1alpha with the molecular mass of 18kDa.
Product information
| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | EK0389 |
| Product category | PicoKine® ELISA Kits |
| Reactive species | Human |
| Tested applications | ELISA |
| Gene name | IL1A |
| Protein name | Interleukin-1 alpha |
| Sample type | cell culture supernatants, serum and plasma ( heparin, EDTA, citrate). |
| Assay range | 4.7 pg/ml - 300 pg/ml |
| Sensitivity | <0.5 pg/ml |
| Specificity | Natural and recombinant human IL-1 alpha |
| Immunogen | Expression system for standard: E.coli; Immunogen sequence: S113-A271 |
| Storage | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| UniProt | P01583 |
| NCBI Gene ID | 3552 |
Available variants
| Conjugation | Size |
|---|---|
| Not applicable | 96 wells/kit, with removable strips. |
Key Facts
| Target | Interleukin-1 alpha |
| Also known as | Hematopoietin 1; IL 1 alpha; IL 1A; IL1; IL-1; IL1 ALPHA; IL-1 alpha; IL1A; IL1F1; IL-1α; Interleukin 1 alpha; interleukin 1, alpha; IL-1A |
| Species reactivity | Human |
| Purity | Natural and recombinant human IL-1 alpha |
| Shelf life | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| Sensitivity | <0.5 pg/ml |
| Detection range | 4.7 pg/ml - 300 pg/ml |
| Sample types |
cell culture supernatantsserum and plasma ( heparinEDTAcitrate).
See sample validation ›
|
Sample Type Validation
4 sample types| Sample Type | SERUM | PLASMA (EDTA) | URINE | CSF | CELL SUPERNATANT |
|---|---|---|---|---|---|
| cell culture supernatants | |||||
| serum and plasma ( heparin | |||||
| EDTA | |||||
| citrate). |
Specifications
Storage & Stability
Compliance & Certifications
Not intended for diagnostic or therapeutic use.