Human HNMT ELISA Kit PicoKine®

Human HNMT ELISA Kit PicoKine® is a research-use ELISA kit from Boster Bio for measuring Histamine N-methyltransferase in Cell culture supernatant, serum and plasma (heparin, EDTA) samples from Human. Use the listed assay range, sample guidance and protocol documents to assess suitability for the intended study.

Human HNMT Kit PicoKine® (96 Tests). Quantitate Human HNMT in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 10 pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.

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