Human HNMT ELISA Kit PicoKine®
ELISA Kit supplied by Boster Bio Read more ›

Product Description
In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.
Product information
| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | EK2216 |
| Product category | PicoKine® ELISA Kits |
| Reactive species | Human |
| Tested applications | ELISA |
| Gene name | HNMT |
| Protein name | Histamine N-methyltransferase |
| Sample type | cell culture supernatants, serum and plasma (heparin, EDTA) |
| Assay range | 62.5 pg/ml - 4,000 pg/ml |
| Sensitivity | <10 pg/ml |
| Specificity | Natural and recombinant human HNMT |
| Immunogen | Expression system for standard: E.coli; Immunogen sequence: A2-A292 |
| Storage | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| UniProt | P50135 |
| NCBI Gene ID | 3176 |
Available variants
| Conjugation | Size |
|---|---|
| Not applicable | 96 wells/kit, with removable strips. |
Key Facts
| Target | Histamine N-methyltransferase |
| Also known as | histamine N methyltransferase; HMT; HNMT; HNMT S1; HNMT S2 |
| Species reactivity | Human |
| Purity | Natural and recombinant human HNMT |
| Shelf life | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| Sensitivity | <10 pg/ml |
| Detection range | 62.5 pg/ml - 4,000 pg/ml |
| Sample types |
cell culture supernatantsserum and plasma (heparinEDTA)
See sample validation ›
|
Sample Type Validation
3 sample types| Sample Type | SERUM | PLASMA (EDTA) | URINE | CSF | CELL SUPERNATANT |
|---|---|---|---|---|---|
| cell culture supernatants | |||||
| serum and plasma (heparin | |||||
| EDTA) |
Specifications
Storage & Stability
Compliance & Certifications
Not intended for diagnostic or therapeutic use.