Human Haptoglobin ELISA Kit PicoKine®

Human Haptoglobin ELISA Kit PicoKine® (96 Tests). Quantitate Human HP in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 20pg/ml . The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Haptoglobin (HP), is a protein that in humans is encoded by the HP gene. Haptoglobin, a plasma glycoprotein that binds free hemoglobin, has a tetrameric structure of 2 alpha and 2 beta polypeptides that are covalently associated by disulfide bonds. Haptoglobin is homologous to serine proteases of the chymotrypsinogen family. In the chimpanzee, there are 3 genes in the haptoglobin family (haptoglobin, HP; haptoglobin-related, HPR; and haptoglobin-primate, HPP), whereas only 2 genes exist in humans (HP and HPR). There are similarities between the primary structures of the alpha chain and of light chains of gamma globulins. The alpha haptoglobin locus is on the long arm of chromosome 16, where its exact cytogenetic location is 16q22.2. A major function of haptoglobin is to bind hemoglobin (Hb) to form a stable Hp-Hb complex and thereby prevent Hb-induced oxidative tissue damage. Haptoglobin is an unusual secretory protein in that it is proteolytically processed in the endoplasmic reticulum and not in the Golgi. The human haptoglobin HP*2 allele contains a 1.7-kb intragenic duplication that arose after a unique nonhomologous recombination between the prototype HP*1 alleles.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK1702
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	HP
Protein name	Haptoglobin
Sample type	cell culture supernatants, serum and plasma (heparin, EDTA).
Assay range	312 pg/ml - 20,000 pg/ml
Sensitivity	<20 pg/ml
Specificity	Natural and recombinant human Haptoglobin
Immunogen	Expression system for standard: NS0; Immunogen sequence: V19-N406
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	P00738
NCBI Gene ID	3240

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.