Human FLT3/FLK2 ELISA Kit PicoKine®

Human FLT3/FLK2 ELISA Kit PicoKine® is a research-use ELISA kit from Boster Bio for measuring Receptor-type tyrosine-protein kinase FLT3 in Cell culture supernatant, lysates, serum and plasma (heparin, EDTA). samples from Human. Use the listed assay range, sample guidance and protocol documents to assess suitability for the intended study.

Human FLT3/FLK2 ELISA Kit PicoKine® (96 Tests). Quantitate Human FLT3 in cell culture supernatants, lysates, serum and plasma (heparin, EDTA). Sensitivity: 50pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Cluster of differentiation antigen 135 (CD135) also known as fms like tyrosine kinase 3 (FLT-3), receptor-type tyrosine-protein kinase FLT3, or fetal liver kinase-2 (Flk2) is a protein that in humans is encoded by the FLT3 gene. It is mapped to 13q12.2. This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.

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