Human FAS/Cd95 ELISA Kit PicoKine®

Human FAS/Cd95 ELISA Kit PicoKine® (96 Tests). Quantitate Human FAS in cell culture supernatants, serum and plasma (heparin, EDTA, citrate). Sensitivity: 3 pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Fas, also known as APO-1, CD95 and TNFRSF6, is a member of the nerve growth factor (NGF)/tumour necrosis factor (TNF) receptor superfamily and mediates apoptosis. The nucleotide sequence of the cDNAs reveales that the molecule coding for the Fas antigen determinant is a 319 amino acid polypeptide with a single transmembrane domain. The extracellular domain is rich in cysteine residue, and shows a similarity to that of human tumor necrosis factor receptors, human nerve growth factor receptor, and human B cell antigen CD40. The APO-1 antigen as defined by the mouse monoclonal antibody anti-APO-1 is previously found to be expressed on the cell surface of activated human T and B lymphocytes and a variety of malignant human lymphoid cell lines. The APO-1 antigen is found to be a membrane glycoprotein of 48-kDa. Fas antigen is expressed and functional on papillary thyroid cancer cells and this may have potential therapeutic significance. Fas can play a role as an inducer of both neurite growth in vitro and accelerates recovery after nerve injury in vivo. The FAS and FASL triggered apoptosis pathway plays an important role in human carcinogenesis.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK0335
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	FAS
Protein name	Tumor necrosis factor receptor superfamily member 6
Sample type	cell culture supernatants, serum and plasma (heparin, EDTA, citrate).
Assay range	31.2 pg/ml - 2,000 pg/ml
Sensitivity	<3 pg/ml
Specificity	Natural and recombinant human sFAS
Immunogen	Expression system for standard: NS0; Immunogen sequence: R17-N173
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	P25445
NCBI Gene ID	355

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.