Human F11 ELISA Kit PicoKine®

Human F11 ELISA Kit PicoKine® (96 Tests). Quantitate Human F11 in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 20 pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Factor XI or plasma thromboplastin antecedent is the zymogen form of factor XIa, one of the enzymes of the coagulation cascade. Like many other coagulation factors, it is a serine protease. In humans, Factor XI is encoded by the F11 gene. This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK2199
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	F11
Protein name	Coagulation factor XI
Sample type	cell culture supernatants, serum and plasma (heparin, EDTA)
Assay range	0.78 ng/ml - 50 ng/ml
Sensitivity	<20 pg/ml
Specificity	Natural and recombinant human F11
Immunogen	Expression system for standard: NS0; Immunogen sequence: E19-V625
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	P03951
NCBI Gene ID	2160

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.