Human F10 ELISA Kit PicoKine®

Human F10 ELISA Kit PicoKine® (96 Tests). Quantitate Human F10 in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 20 pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK2198
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	F10
Protein name	Coagulation factor X
Sample type	cell culture supernatants, serum and plasma (heparin, EDTA)
Assay range	0.78 ng/ml - 50 ng/ml
Sensitivity	<20 pg/ml
Specificity	Natural and recombinant human F10
Immunogen	Expression system for standard: NS0; Immunogen sequence: L24-K488
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	P00742
NCBI Gene ID	2159

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.