Human Eotaxin / CCL11 ELISA Kit PicoKine®

Human Eotaxin / CCL11 ELISA Kit PicoKine® is a research-use ELISA kit from Boster Bio for measuring Eotaxin in Cell culture supernatant, serum and plasma (citrate, EDTA). samples from Human. Use the listed assay range, sample guidance and protocol documents to assess suitability for the intended study.

Human Eotaxin / CCL11 ELISA Kit PicoKine® (96 Tests). Quantitate Human CCL11 in cell culture supernatants, serum and plasma (citrate, EDTA). Sensitivity: 2pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Eotaxin, also known as CCL11, is a potent inducer of eosinophil chemotaxis and is considered as a selective ligand of the CC chemokine receptor 3 (CCR3), which is expressed on eosinophils, basophils, and Th2 lymphocytes. Eotaxin is assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. The gene maps to chromosome 17 and is expressed constitutively at high levels in small intestine and colon, and at lower levels in various other tissues. The deduced mature protein sequence is 66% identical to human monocyte chemoattractant protein-1, and 60% identical to guinea pig eotaxin. Recombinant human eotaxin produced in insect cells induces a calcium flux response in normal human eosinophils, but not in neutrophils or monocytes. The human eotaxin gene is cloned and found to be 61.8 and 63.2% identical at the amino acid level to guinea pig and mouse eotaxin.

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