Human Diablo/SMAC ELISA Kit EZ-Set™ (DIY Antibody Pairs)

Human Diablo/SMAC ELISA Kit EZ-Set™ (DIY Antibody Pairs) (antibody pairs and standards for assay development). Quantitate Human DIABLO in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).

Diablo homolog, mitochondrial, also known as second mitochondria-derived activator of caspases (SMAC), is a protein that in humans is encoded by the DIABLO gene ( IAP binding protein with low pI). It is mapped to 12q24.31. DIABLO can bind mammalian IAP homolog A (MIHA, or API3) and can also interact with MIHB, MIHC, and OpIAP, the baculoviral IAP. This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Over expression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EZ0838
Product category	EZ-Set™ ELISA Kits (Ab Pairs)
Reactive species	Human
Tested applications	ELISA
Gene name	DIABLO
Protein name	Diablo IAP-binding mitochondrial protein
Sample type	cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).
Assay range	31.2 pg/ml - 2,000 pg/ml
Specificity	Natural and recombinant human Diablo/SMAC
Immunogen	Expression system for standard: E.coli; Immunogen sequence: A56-D239
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	Q9NR28
NCBI Gene ID	56616

Available variants

Conjugation	Size
Not applicable	5 plates/kit