Human Cystatin C ELISA Kit EZ-Set™ (DIY Antibody Pairs)

Human Cystatin C ELISA Kit EZ-Set™ (DIY Antibody Pairs) (antibody pairs and standards for assay development). Quantitate Human CST3 in cell culture supernatants, serum, plasma (heparin, EDTA), saliva, urine and human milk.

Cystatin C or cystatin 3 (formerly gamma trace, post-gamma-globulin or neuroendocrine basic polypeptide), a protein encoded by the CST3 gene, was originally described as a constituent of normal cerebrospinal fluid (CSF) and of urine from patients with renal failure.1 Cystatin 3 has a low molecular weight (approximately 13.3 kilodaltons), and it is removed from the bloodstream by glomerular filtration in the kidneys. In humans, all cells with a nucleus (cell core containing the DNA) produce cystatin C as a chain of 120 amino acids. It is found in virtually all tissues and bodily fluids. Cystatin C, which belongs to the type II cystatin gene family, is a potent inhibitor of lysosomal proteinases2 (enzymes from a special subunit of the cell that break down proteins) and probably one of the most important extracellular inhibitors of cysteine proteases3 (it prevents the breakdown of proteins outside the cell by a specific type of protein degrading enzymes). Moreover, cystatin C is involved in network reorganization in the epileptic dentate gyrus.4

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EZ0678
Product category	EZ-Set™ ELISA Kits (Ab Pairs)
Reactive species	Human
Tested applications	ELISA
Gene name	CST3
Protein name	Cystatin-C
Sample type	cell culture supernatants, serum, plasma (heparin, EDTA) , saliva, urine and human milk.
Assay range	312 pg/ml - 20,000 pg/ml
Specificity	Natural and recombinant human IL-32
Immunogen	Expression system for standard: NS0; Immunogen sequence: M1-A146
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	P01034
NCBI Gene ID	1471

Available variants

Conjugation	Size
Not applicable	5 plates/kit