Human Cystatin B/CSTB ELISA Kit PicoKine®

Human Cystatin B ELISA Kit PicoKine® (96 Tests). Quantitate Human CSTB in cell culture supernatants, serum, plasma (heparin, EDTA) , saliva, urine and human milk. Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Cystatin B (CSTB), also called STFB, is a small protein that is a member of the superfamily of cysteine protease inhibitors. It has been isolated from human spleen and liver and its amino acid sequence has been fully determined. The cystatin B gene is located on 21q22.3. It is widely distributed and is localized mostly intracellularly, but has been found extracellularly. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Its role is thought to be as a protector against the proteinases leaking from lysosomes. A cystatin B multiprotein complex might have a specific cerebellar function, and that the loss of this function might contribute to the etiopathogenesis of EPM1. Upon differentiation to myotubes, CSTB becomes excluded from the nucleus and lysosomes, suggesting that the subcellular distribution of CSTB is dependent on the differentiation status of the cell.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK1205
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	CSTB
Protein name	Cystatin-B
Sample type	cell culture supernatants, serum, plasma (heparin, EDTA) , saliva, urine and human milk.
Assay range	62.5 pg/ml - 4,000 pg/ml
Sensitivity	<10 pg/ml
Specificity	Natural and recombinant human Cystatin B
Immunogen	Expression system for standard: E.coli; Immunogen sequence: M2-F98
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	P04080
NCBI Gene ID	1476

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.