Human CXCL16 ELISA Kit EZ-Set™ (DIY Antibody Pairs)

Human CXCL16 ELISA Kit EZ-Set™ (DIY Antibody Pairs) (antibody pairs and standards for assay development). Quantitate Human CXCL16 in cell culture supernatants, cell lysates, tissue homogenates, serum and plasma (heparin, EDTA).

Chemokine (C-X-C motif) ligand 16 (CXCL16) is a small cytokine belonging to the CXC chemokine family. Larger than other chemokines (with 254 amino acids), CXCL16 is composed of a CXC chemokine domain, a mucin-like stalk, a transmembrane domain and a cytoplasmic tail containing a potential tyrosine phosphorylation site that may bind SH2. These are unusual features for a chemokine, and allow CXCL16 to be expressed as a cell surface bound molecule, as well as a soluble chemokine. CXCL16 is produced by dendritic cells found in the T cell zones of lymphoid organs, and by cells found in the red pulp of the spleen. Cells that bind and migrate in response to CXCL16 include several subsets of T cells, and natural killer T (NKT) cells. CXCL16 interacts with the chemokine receptorCXCR6, also known as Bonzo. The novel CXC-chemokine ligand 16 (CXCL16) functions as transmembrane adhesion molecule on the surface of APCs and as a soluble chemoattractant for activated T cells. Expression of CXCL16 is induced by the inflammatory cytokines IFN-gamma and TNF-alpha. The gene for human CXCL16 is located on chromosome 17.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EZ0741
Product category	EZ-Set™ ELISA Kits (Ab Pairs)
Reactive species	Human
Tested applications	ELISA
Gene name	CXCL16
Protein name	C-X-C motif chemokine 16
Sample type	cell culture supernatants, cell lysates, tissue homogenates, serum and plasma (heparin, EDTA).
Assay range	93.7 pg/ml - 6,000 pg/ml
Specificity	Natural and recombinant human CXCL16
Immunogen	Expression system for standard: E.coli; Immunogen sequence: N49-P137
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	Q9H2A7
NCBI Gene ID	58191

Available variants

Conjugation	Size
Not applicable	5 plates/kit