Human Corin ELISA Kit PicoKine®

Human Corin ELISA Kit PicoKine® (96 Tests). Quantitate Human CORIN in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Atrial natriuretic peptide-converting enzyme, also called CRN or ATC2, is a protein that in humans is encoded by the CORIN gene. It is mapped to 4p12. This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. It has been found that Corin is the pro-ANP-converting enzyme and that Corin-mediated pro-ANP activation may play a role in regulating blood pressure. What’s more, Corin and ANP are essential for physiologic changes at the maternal-fetal interface. This protein may also function as a pro-brain-type natriuretic peptide convertase. Corin gene mutations which cause Corin to impair activity might be an underlying mechanism in hypertension.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK1283
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	CORIN
Protein name	Atrial natriuretic peptide-converting enzyme
Sample type	cell culture supernatants, serum and plasma (heparin, EDTA).
Assay range	62.5 pg/ml - 4,000 pg/ml
Sensitivity	<10 pg/ml
Specificity	Natural and recombinant human Corin
Immunogen	Expression system for standard: NS0; Immunogen sequence: S67-N1042
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	Q9Y5Q5
NCBI Gene ID	10699

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.