Human Chitotriosidase/CHIT1 ELISA Kit PicoKine®

Human Chitotriosidase/CHIT1 ELISA Kit PicoKine® (96 Tests). Quantitate Human CHIT1 in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 50pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Chitotriosidase encoded by the CHIT1 gene is a member of the chitinase family that is selectively expressed in activated tissue macrophages. This gene is mapped to 1q32.1. Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK2032
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	CHIT1
Protein name	Chitotriosidase-1
Sample type	cell culture supernatants, serum and plasma (heparin, EDTA).
Assay range	312 pg/ml - 20,000 pg/ml
Sensitivity	<50 pg/ml
Specificity	Natural and recombinant human CHIT1
Immunogen	Expression system for standard: NS0; Immunogen sequence: A22-N466
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	Q13231
NCBI Gene ID	1118

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.