Human BMP-10 ELISA Kit PicoKine®

Human BMP-10 ELISA Kit PicoKine® (96 Tests). Quantitate Human BMP10 in cell culture supernatants, serum and plasma (heparin, EDTA, citrate ). Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. This gene is mapped to 2p13.3. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. BMP-10 plays a crucial role in the development of the embryonic heart by acting to stimulate and maintain cardiomyocyte proliferation. It can signal through various receptor complexes usually containing BMPR-1A, BMPR-1B, ALK1, ALK3, or ALK6. The interaction of BMP-10 with its specific receptors can induce signaling initiated by the phosphorylation of SMAD transcription factors, including SMAD1, SMAD5, or SMAD8, but can also induce SMAD independent processes. BMP-10 is structurally related to BMP-9, and both can inhibit endothelial cell proliferation and migration. Recombinant human BMP-10 is a 24.4 kDa homodimeric disulfide-linked protein consisting of two 108 amino acid subunits, which correspond to amino acid residues 317 to 424 of the full-length BMP-10 precursor.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK1808
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	BMP10
Protein name	Bone morphogenetic protein 10
Sample type	cell culture supernatants, serum and plasma (heparin, EDTA, citrate ).
Assay range	15.6 pg/ml - 1,000 pg/ml
Sensitivity	<10 pg/ml
Specificity	Natural and recombinant human BMP-10
Immunogen	Expression system for standard: NS0; Immunogen sequence: N314-R421
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	O95393
NCBI Gene ID	27302

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.