Human Annexin A1 PicoKine® Quick ELISA Kit

Human Annexin A1 PicoKine® Quick ELISA Kit (90 minutes, 96 Tests). Quantitate Human ANXA1 in cell culture supernatants, serum and plasma (heparin, EDTA, citrate). Sensitivity: 100pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

ANXA1, also known as lipocortin I or Annexin A1, is a protein that in humans is encoded by the ANXA1 gene. It is mapped to 9q21.13. ANXA1 belongs to a family of Ca (2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. ANXA1 protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Lower peptide concentrations possibly found in inflammatory situations elicit Ca (2+) transients without fully activating the mitogen-activated protein kinase pathway. This causes a specific inhibition of the transendothelial migration of neutrophils and a desensitization of neutrophils toward a chemoattractant challenge. These findings identified ANXA1 peptides as novel, endogenous FPR ligands and established a mechanistic basis of ANXA1-mediated antiinflammatory effects.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	FEK1745
Product category	Quick ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	CST3
Protein name	Annexin A1
Sample type	cell culture supernatants, serum and plasma (heparin, EDTA, citrate)
Assay range	156 pg/ml - 10,000 pg/ml
Sensitivity	<100 pg/ml
Specificity	Natural and recombinant Human ANXA1
Immunogen	Expression system for standard: NS0; Immunogen sequence: A2-N346
Storage	Store at 4°C for 6 months. (Ships with gel ice, can store for up to 3 days in room temperature. Refrigerate upon receipt.)
UniProt	P04083
NCBI Gene ID	301

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.