Human AGT/Serpin A8/Angiotensinogen ELISA Kit PicoKine®
ELISA Kit supplied by Boster Bio Read more ›

Product Description
AGT (ANGIOTENSINOGEN), also called SERPINA8, is an α-2-globulin that is produced constitutively and released into the circulation mainly by the liver. ATG is a member of the serpin family, although it is not known to inhibit other enzymes, unlike most serpins. Angiotensinogen is also known as renin substrate. The AGT gene is mapped on 1q42.2. And the human angiotensinogen gene contains 5 exons. The expression of AGT and enzymes required for its conversion to angiotensin II in human adipose tissue. Mutations in this AGT gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
Product information
| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | EK1465 |
| Product category | PicoKine® ELISA Kits |
| Reactive species | Human |
| Tested applications | ELISA |
| Gene name | AGT |
| Protein name | Angiotensinogen |
| Sample type | cell culture supernatants, serum and plasma (EDTA). |
| Assay range | 312 pg/ml - 20,000 pg/ml |
| Sensitivity | <10 pg/ml |
| Specificity | Natural and recombinant human AGT |
| Immunogen | Expression system for standard: NS0; Immunogen sequence: D34-A485 |
| Storage | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| UniProt | P01019 |
| NCBI Gene ID | 183 |
Available variants
| Conjugation | Size |
|---|---|
| Not applicable | 96 wells/kit, with removable strips. |
Key Facts
| Target | Angiotensinogen |
| Also known as | AGT; Ang I Angiotensin 2; Ang II Angiotensin 3; Ang III; Angiotensin; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensinogen; ANHU; Des Asp1 angiotensin II; Serpin A8; SERPINA8 |
| Species reactivity | Human |
| Purity | Natural and recombinant human AGT |
| Shelf life | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| Sensitivity | <10 pg/ml |
| Detection range | 312 pg/ml - 20,000 pg/ml |
| Sample types |
cell culture supernatantsserum and plasma (EDTA).
See sample validation ›
|
Sample Type Validation
2 sample types| Sample Type | SERUM | PLASMA (EDTA) | URINE | CSF | CELL SUPERNATANT |
|---|---|---|---|---|---|
| cell culture supernatants | |||||
| serum and plasma (EDTA). |
Specifications
Storage & Stability
Compliance & Certifications
Not intended for diagnostic or therapeutic use.