Human Aggrecan/ACAN ELISA Kit PicoKine®
ELISA Kit supplied by Boster Bio Read more ›
Product Description
Aggrecan, also known as cartilage-specific proteoglycan core protein (CSPCP) or chondroitin sulfate proteoglycan 1, is a protein that in humans is encoded by the ACAN gene. It is a critical component for cartilage structure and the function of joints. Aggrecan provides intervertebral disc and cartilage with the ability to resist compressive loads. The localized high concentrations of aggrecan provide the osmotic properties necessary for normal tissue function with the GAGs producing the swelling pressure that counters compressive loads on the tissue. This functional ability is dependent on a high GAG/aggrecan concentration being present in the tissue extracellular matrix. Also, Aggrecan plays an important role in the organization of the extracellular spaces between neurons in the brain.
Product information
| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | EK0909 |
| Product category | PicoKine® ELISA Kits |
| Reactive species | Human |
| Tested applications | ELISA |
| Gene name | ACAN |
| Protein name | Aggrecan core protein |
| Sample type | cell culture supernatants, serum and urine. |
| Assay range | 1.56 ng/ml - 100 ng/ml |
| Sensitivity | <50 pg/ml |
| Specificity | Natural and recombinant human Aggrecan |
| Immunogen | Expression system for standard: NS0; Immunogen sequence: V20-R675 |
| Storage | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| UniProt | P16112 |
| NCBI Gene ID | 176 |
Available variants
| Conjugation | Size |
|---|---|
| Not applicable | 96 wells/kit, with removable strips. |
Key Facts
| Target | Aggrecan core protein |
| Also known as | ACAN; AGC1; AGCAN; aggrecan; CSPG1; CSPGCP; MSK16; SEDK |
| Species reactivity | Human |
| Purity | Natural and recombinant human Aggrecan |
| Shelf life | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| Sensitivity | <50 pg/ml |
| Detection range | 1.56 ng/ml - 100 ng/ml |
| Sample types |
cell culture supernatantsserum and urine.
See sample validation ›
|
Sample Type Validation
2 sample types| Sample Type | SERUM | PLASMA (EDTA) | URINE | CSF | CELL SUPERNATANT |
|---|---|---|---|---|---|
| cell culture supernatants | |||||
| serum and urine. |
Specifications
Storage & Stability
Compliance & Certifications
Not intended for diagnostic or therapeutic use.