Human ADAM12 PicoKine® Quick ELISA Kit
ELISA Kit supplied by Boster Bio Read more ›

Product Description
ADAM12 (Disintegrin and metalloproteinase domain-containing protein 12), also known as MLTN, is an enzyme that in humans is encoded by the ADAM12 gene. This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene has two alternatively spliced transcripts: a shorter secreted form and a longer membrane-bound form. The shorter form is found to stimulate myogenesis. By RT-PCR and immunoblot analyses that expression of mouse Adam12 increases during muscle regeneration, while the levels of other ADAMs remain constant. Immunofluorescence analysis revealed staining of small, newly formed muscle fibers in regenerating but not normal adult muscle cells. By using of fluorescence in situ hybridization, the ADAM12 gene is mapped to human chromosome 10q26.3.
Product information
| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | FEK0934 |
| Product category | Quick ELISA Kits |
| Reactive species | Human |
| Tested applications | ELISA |
| Gene name | ADAM12 |
| Protein name | Disintegrin and metalloproteinase domain-containing protein 12 |
| Sample type | cell culture supernatants, serum, plasma (heparin) and urine. |
| Assay range | 156 pg/ml - 10,000 pg/ml |
| Sensitivity | <10 pg/ml |
| Specificity | Natural and recombinant human ADAM12 |
| Immunogen | Expression system for standard: CHO; Immunogen sequence: R29-S513 |
| Storage | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| UniProt | O43184 |
| NCBI Gene ID | 8038 |
Available variants
| Conjugation | Size |
|---|---|
| Not applicable | 96 wells/kit, with removable strips. |
Key Facts
| Target | Disintegrin and metalloproteinase domain-containing protein 12 |
| Also known as | ADAM 12; ADAM12; MCMP; MCMPMltna; Meltrin alpha; MLTN; MLTNA |
| Species reactivity | Human |
| Purity | Natural and recombinant human ADAM12 |
| Shelf life | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| Sensitivity | <10 pg/ml |
| Detection range | 156 pg/ml - 10,000 pg/ml |
| Sample types |
cell culture supernatantsserumplasma (heparin) and urine.
See sample validation ›
|
Sample Type Validation
3 sample types| Sample Type | SERUM | PLASMA (EDTA) | URINE | CSF | CELL SUPERNATANT |
|---|---|---|---|---|---|
| cell culture supernatants | |||||
| serum | |||||
| plasma (heparin) and urine. |
Specifications
Storage & Stability
Compliance & Certifications
Not intended for diagnostic or therapeutic use.