TP53 Break Apart FISH Probe Reagent

TP53 encodes p53, a central tumour suppressor involved in DNA damage response, cell-cycle control and apoptosis; deletion studies are common in cancer cytogenetics research.

The break-apart design is used to investigate rearrangements involving TP53, where separation of differently labelled probe signals can indicate disruption of the target locus in prepared research specimens.

FISH probes are applied to fixed cells or prepared tissue sections where genomic targets remain spatially preserved, making them useful for molecular cytogenetics research, tumour biology studies and verification of structural or numerical chromosomal changes.

This product is supplied as a 100µL/10 Tests RUO probe reagent from Wuhan HealthCare Biotechnology. DAPI included It should be stored sealed, protected from light and handled using appropriate FISH sample preparation conditions.