Primary Antibody ISO 9001|ABMIUM Verified™
ABM99823

IL-17RB rabbit pAb

ISO 9001|ABMIUM Verified™|Antibody

IL-17RB rabbit pAb from ELK Biotechnology Read more ›

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IL-17RB rabbit pAb
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IL-17RB rabbit pAb

Product Description

IL-17RB rabbit pAb is an ELK Biotechnology antibody for research workflows involving IL-17RB.

Background

The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq, Jul 2008],

Additional antibody information

Specificity IL-17RB Polyclonal Antibody detects endogenous levels of IL-17RB
Validation evidence captions Western Blot analysis of HEPG2 3T3 cells using IL-17RB Polyclonal Antibody diluted at 1:1000. Secondary antibody(catalog#:RS0002) was diluted at 1:20000

Key Facts

Product type Primary Antibody Target: IL-17RB
Target IL-17RB
Also known as Interleukin-17 receptor B (IL-17 receptor B) (IL-17RB) (Cytokine receptor-like 4) (IL-17 receptor homolog 1) (IL-17Rh1) (IL17Rh1) (Interleukin-17B receptor) (IL-17B receptor)
Concentration 1 mg/ml
Working concentration WB 1:500-2000, ELISA 1:10000-20000
Species reactivity Human;Rat;Mouse;
Observed band 55kD
Cellular localization Isoform 1: Cell membrane; Single-pass type I membrane protein.; Isoform 2: Secreted.
Purity The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form / buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Research area >>Cytokine-cytokine receptor interaction;>>IL-17 signaling pathway
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Conjugation Unconjugated
Tested applications
WBELISA
Dilution range WB 1:500-2000, ELISA 1:10000-20000
Immunogen Synthesized peptide derived from IL-17RB at AA range: 251-300
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reactivity & Application Validation

3 speciess
ABMIUM Validated™ ABMIUM Verified™ Expected Performance Not suitable
SpeciesWBIHCIFELISAIPFCMCHIP
Human
Rat
Mouse
ABMIUM Validated™ WB
Species Dilution Notes
Human WB 1:500-2000
Rat
Mouse
ABMIUM Validated™ ELISA
Species Dilution Notes

Specifications

Target
IL-17RB
Also known as
Interleukin-17 receptor B (IL-17 receptor B) (IL-17RB) (Cytokine receptor-like 4) (IL-17 receptor homolog 1) (IL-17Rh1) (IL17Rh1) (Interleukin-17B receptor) (IL-17B receptor)
Concentration
1 mg/ml
Working concentration
WB 1:500-2000, ELISA 1:10000-20000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form / buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Species reactivity
Human;Rat;Mouse;
Tested applications
WBELISA
Immunogen
Synthesized peptide derived from IL-17RB at AA range: 251-300
Observed band
55kD
Cellular localization
Isoform 1: Cell membrane; Single-pass type I membrane protein.; Isoform 2: Secreted.
Dilution range
WB 1:500-2000, ELISA 1:10000-20000
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage & Stability

Long-term storage
-20°C/1 year
Storage conditions
-20°C/1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Compliance & Certifications

ISO 9001
ISO 9001:2015 Certified

Manufactured under ISO 9001:2015 quality management standards.

RUO
For Research Use Only

Not intended for diagnostic or therapeutic use.

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