CD19 (phospho Tyr531) rabbit pAb from ELK Biotechnology
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CD19 (phospho Tyr531) rabbit pAb is a research-use antibody from ELK Biotechnology for studying CD19 in WB, ELISA workflows with listed reactivity for Human, Mouse, Monkey. Specifications and supporting documents below should be reviewed when planning the experiment.
Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. [provided by RefSeq, Jul 2008],
| Specificity | Phospho-CD19 (Y531) Polyclonal Antibody detects endogenous levels of CD19 protein only when phosphorylated at Y531. |
|---|---|
| Validation evidence captions | Western blot analysis of lysates from COS7 cells treated with Serum 10% 30', using CD19 (Phospho-Tyr531) Antibody. The lane on the right is blocked with the phospho peptide. |
Fully tested in-house by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Mouse | |||||||
| Monkey |
This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
CD19 molecule (CD19), also known as B-lymphocyte antigen CD19, is a B-cell surface glycoprotein and signalling coreceptor. This guide connects human NCBI Gene 930, UniProtKB P15391 and ABMIUM catalogue products associated with CD19.
Biological function: CD19 functions as a coreceptor for the B-cell antigen receptor complex, lowering the threshold for antigen-triggered B-cell activation. CD19 signalling can activate phosphatidylinositol 3-kinase pathways and mobilise intracellular calcium, supporting normal B-cell differentiation, proliferation and antibody responses.
