L-type Ca++ CP γ1 rabbit pAb
L-type Ca++ CP γ1 rabbit pAb from ELK Biotechnology Read more ›
Product Description
L-type Ca++ CP γ1 rabbit pAb is an ELK Biotechnology antibody for research workflows involving L-type Ca++ CP γ1.
Background
calcium voltage-gated channel auxiliary subunit gamma 1(CACNG1) Homo sapiens Voltage-dependent calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of two known gamma subunit proteins. This particular gamma subunit is part of skeletal muscle 1,4-dihydropyridine-sensitive calcium channels and is an integral membrane protein that plays a role in excitation-contraction coupling. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members that function as transmembrane AMPA receptor regulatory proteins (TARPs). [provided by RefSeq, Dec 2010],
Additional antibody information
| Specificity | L-type Ca++ CP γ1 Polyclonal Antibody detects endogenous levels of L-type Ca++ CP γ1 protein. |
|---|---|
| Validation evidence captions | Western blot analysis of CACNG1 Antibody. The lane on the right is blocked with the CACNG1 peptide. | Western blot analysis of the lysates from COLO205 cells using CACNG1 antibody. |
Key Facts
| Target | L-type Ca++ CP γ1 |
| Also known as | CACNG1; CACNLG; Voltage-dependent calcium channel gamma-1 subunit; Dihydropyridine-sensitive L-type; skeletal muscle calcium channel subunit gamma |
| Concentration | 1 mg/ml |
| Working concentration | Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Species reactivity | Human;Mouse;Rat |
| Observed band | 25kD |
| Cellular localization | Cell membrane, sarcolemma ; Multi-pass membrane protein . |
| Purity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Form / buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Research area | >>MAPK signaling pathway;>>Cardiac muscle contraction;>>Adrenergic signaling in cardiomyocytes;>>Oxytocin signaling pathway;>>Hypertrophic cardiomyopathy;>>Arrhythmogenic right ventricular cardiomyopathy;>>Dilated cardiomyopathy |
| Host species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Tested applications |
WBELISA |
| Dilution range | Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CACNG1. AA range:137-186 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Reactivity & Application Validation
3 speciess| Species | WB | IHC | IF | ELISA | IP | FCM | CHIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Mouse | |||||||
| Rat |
| Species | Dilution | Notes |
|---|---|---|
| Human | Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications. | — |
| Mouse | — | — |
| Rat | — | — |
| Species | Dilution | Notes |
|---|
Specifications
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Not intended for diagnostic or therapeutic use.