Collaborator ELK Biotechnology
Primary AntibodyISO 9001:2015
ABM99146

PIPOX rabbit pAb

ISO 9001|ABMIUM Verified™|Antibody

PIPOX rabbit pAb from ELK Biotechnology Read more ›

PIPOX rabbit pAb
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PIPOX rabbit pAb

Product Description

PIPOX rabbit pAb is a research-use antibody from ELK Biotechnology for studying PIPOX in WB, IHC, ELISA workflows with listed reactivity for Human, Rat, Mouse. Specifications and supporting documents below should be reviewed when planning the experiment.

Background

catalytic activity:L-pipecolate + O(2) = 2,3,4,5-tetrahydropyridine-2-carboxylate + H(2)O(2).,catalytic activity:Sarcosine + H(2)O + O(2) = glycine + formaldehyde + H(2)O(2).,cofactor:Binds 1 FAD per subunit.,function:Metabolizes sarcosine, L-pipecolic acid and L-proline.,similarity:Belongs to the MSOX/MTOX family.,subunit:Monomer.,

Additional antibody information

Specificity PIPOX Polyclonal Antibody detects endogenous levels of PIPOX protein.
Validation evidence captions Western Blot analysis of 3T3 cells using PIPOX Polyclonal Antibody | Western blot analysis of lysates from NIH/3T3 and RAW264.7 cells, using PIPOX Antibody. The lane on the right is blocked with the synthesized peptide. | Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).

Key Facts

Product typePrimary Antibody Target: PIPOX
Collaborator ELK Biotechnology
Partner model ES6510
Target PIPOX
Research areas>>Glycine, serine and threonine metabolism, >>Lysine degradation, >>Metabolic pathways, >>Peroxisome
Reactivity Human,Rat,Mouse
Applications WB,IHC,ELISA
ConjugationUnconjugated
Dilution rangeWB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Host Rabbit
Clonality Polyclonal
Isotype IgG
Immunogen The antiserum was produced against synthesized peptide derived from human PIPOX. AA range:257-306
Concentration 1 mg/ml
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay type Antibody validation/application
Expression system Expressed in the liver and kidney.
Purity The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Application Validation Matrix

3 speciess
ABMIUM Validated™ ABMIUM Verified™ Expected Performance Not suitable
SpeciesWBIHCIFELISAIPFCMChIP
Human
Rat
Mouse
ABMIUM Validated™ WB
Species Dilution Notes
Human WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Rat
Mouse
ABMIUM Validated™ IHC
Species Dilution Notes
ABMIUM Validated™ ELISA
Species Dilution Notes

Specifications

Target
PIPOX
Also known as
PIPOX; LPIPOX; PSO; Peroxisomal sarcosine oxidase; PSO; L-pipecolate oxidase; L-pipecolic acid oxidase
Concentration
1 mg/ml
Working concentration
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form / buffer
Liquid
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Species reactivity
Human,Rat,Mouse
Tested applications
WBIHCELISA
Immunogen
The antiserum was produced against synthesized peptide derived from human PIPOX. AA range:257-306
Observed band
44kD
Cellular localization
Peroxisome .
Dilution range
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage & Stability

Long-term storage
'-20°C/1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Compliance & Certifications

ABMIUM
ABMIUM Verified

Collaborator meets ABMIUM quality standards and overall product performance standards have been met.

ISO
ISO 9001

Quality management certification.

RUO
Research Use Only

For research applications. Not for diagnostic use.

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