FGF-13 rabbit pAb
FGF-13 rabbit pAb from ELK Biotechnology Read more ›
Product Description
FGF-13 rabbit pAb is an ELK Biotechnology antibody for research workflows involving FGF-13.
Background
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked mental retardation mapping to this region. Alternative splicing of this gene at the 5' end results in several transcript variants encoding different isoforms with different N-termini. [provided by RefSeq, Nov 2008],
Additional antibody information
| Specificity | FGF-13 Polyclonal Antibody detects endogenous levels of FGF-13 protein. |
|---|---|
| Validation evidence captions | Western Blot analysis of JK cells using FGF-13 Polyclonal Antibody diluted at 1:500 | Western blot analysis of the lysates from Jurkat cells using FGF13 antibody. |
Key Facts
| Target | FGF-13 |
| Also known as | FGF13; FHF2; Fibroblast growth factor 13; FGF-13; Fibroblast growth factor homologous factor 2; FHF-2 |
| Concentration | 1 mg/ml |
| Working concentration | Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Species reactivity | Human;Mouse;Rat |
| Observed band | 28kD |
| Cellular localization | Isoform 1: Nucleus .; Isoform 2: Cytoplasm . Nucleus .; Isoform 3: Cytoplasm . Nucleus .; Isoform 4: Cytoplasm . Nucleus .; Isoform 5: Cytoplasm . Nucleus .; Cell projection, filopodium . Cell projection, growth cone . Cell projection, dendrite . Cell membrane, sarcolemma . Cytoplasm . Not secreted. Localizes to the lateral membrane and intercalated disks of myocytes. . |
| Purity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Form / buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Research area | Antibody Research |
| Host species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Tested applications |
WBELISA |
| Dilution range | Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human FGF13. AA range:154-203 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Reactivity & Application Validation
3 speciess| Species | WB | IHC | IF | ELISA | IP | FCM | CHIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Mouse | |||||||
| Rat |
| Species | Dilution | Notes |
|---|---|---|
| Human | Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications. | — |
| Mouse | — | — |
| Rat | — | — |
| Species | Dilution | Notes |
|---|
Specifications
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Not intended for diagnostic or therapeutic use.