Cathepsin G rabbit pAb from ELK Biotechnology Read more ›
Cathepsin G rabbit pAb is a research-use antibody from ELK Biotechnology for studying Cathepsin G in WB, ELISA workflows with listed reactivity for Human, Rat, Mouse. Specifications and supporting documents below should be reviewed when planning the experiment.
The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. In addition, the encoded protein is antimicrobial, with bacteriocidal activity against S. aureus and N. gonorrhoeae. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq, Sep 2014],
| Specificity | Cathepsin G Polyclonal Antibody detects endogenous levels of Cathepsin G protein. |
|---|---|
| Validation evidence captions | Western Blot analysis of COLO205 cells using Cathepsin G Polyclonal Antibody | Western blot analysis of lysate from COLO cells, using Cathepsin?G antibody. |
| Collaborator | ELK Biotechnology |
| Partner model | ES4900 |
| Target | Cathepsin G |
| Research areas | >>Neuroactive ligand-receptor interaction, >>Lysosome, >>Neutrophil extracellular trap formation, >>Renin-angiotensin system, >>Amoebiasis, >>Systemic lupus erythematosus |
| Reactivity | Human,Rat,Mouse |
| Applications | WB,ELISA |
| Conjugation | Unconjugated |
| Dilution range | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Cathepsin G. AA range:67-116 |
| Concentration | 1 mg/ml |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Assay type | Antibody validation/application |
| Expression system | Expressed in neutrophils (at protein level) (PubMed:3799965). Expressed in B cells (PubMed:15100291). |
| Purity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Rat | |||||||
| Mouse |
| Species | Dilution | Notes |
|---|---|---|
| Human | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. | — |
| Rat | — | — |
| Mouse | — | — |
| Species | Dilution | Notes |
|---|
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
Quality management certification.
For research applications. Not for diagnostic use.
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