Collaborator ELK Biotechnology
Primary AntibodyISO 9001:2015
ABM98402

PC-PLD4 rabbit pAb

ISO 9001|ABMIUM Verified™|Antibody

PC-PLD4 rabbit pAb from ELK Biotechnology Read more ›

PC-PLD4 rabbit pAb
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PC-PLD4 rabbit pAb

Product Description

PC-PLD4 rabbit pAb is a research-use antibody from ELK Biotechnology for studying PLD4 in WB, IHC workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.

Background

catalytic activity:A phosphatidylcholine + H(2)O = choline + a phosphatidate.,similarity:Belongs to the phospholipase D family.,similarity:Contains 2 PLD phosphodiesterase domains.,

Additional antibody information

Specificity PC-PLD4 Polyclonal Antibody detects endogenous levels of PC-PLD4 protein.
Validation evidence captions Western Blot analysis of Jurkat cells using PC-PLD4 Polyclonal Antibody | Western blot analysis of lysates from Jurkat cells, using PLD4 Antibody. The lane on the right is blocked with the synthesized peptide. | Western blot analysis of the lysates from K562 cells using PLD4 antibody. | Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).

Key Facts

Product typePrimary Antibody Target: PLD4
Collaborator ELK Biotechnology
Partner model ES4701
Target PLD4
Research areas>>Glycerophospholipid metabolism, >>Ether lipid metabolism, >>Metabolic pathways
Reactivity Human,Mouse,Rat
Applications WB,IHC
ConjugationUnconjugated
Dilution rangeWB 1:500-2000;IHC-p 1:50-300
Host Rabbit
Clonality Polyclonal
Isotype IgG
Immunogen The antiserum was produced against synthesized peptide derived from human PLD4. AA range:457-506
Concentration 1 mg/ml
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay type Antibody validation/application
Expression system B-cell,T-cell,
Purity The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Application Validation Matrix

3 speciess
ABMIUM Validated™ ABMIUM Verified™ Expected Performance Not suitable
SpeciesWBIHCIFELISAIPFCMChIP
Human
Mouse
Rat
ABMIUM Validated™ WB
Species Dilution Notes
Human WB 1:500-2000;IHC-p 1:50-300
Mouse
Rat
ABMIUM Validated™ IHC
Species Dilution Notes

Specifications

Target
PLD4
Also known as
PLD4; C14orf175; Phospholipase D4; PLD 4; Choline phosphatase 4; Phosphatidylcholine-hydrolyzing phospholipase D4
Concentration
1 mg/ml
Working concentration
WB 1:500-2000;IHC-p 1:50-300
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form / buffer
Liquid
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Species reactivity
Human,Mouse,Rat
Tested applications
WBIHC
Immunogen
The antiserum was produced against synthesized peptide derived from human PLD4. AA range:457-506
Observed band
50kD
Cellular localization
Endoplasmic reticulum membrane ; Single-pass type II membrane protein . Golgi apparatus, trans-Golgi network membrane ; Single-pass type II membrane protein . Nucleus . Early endosome . Cytoplasmic vesicle, phagosome . Activation of microglia induces translocation of PLD4 from the nucleus to the phagosomes. .
Dilution range
WB 1:500-2000;IHC-p 1:50-300
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage & Stability

Long-term storage
'-20°C/1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Compliance & Certifications

ABMIUM
ABMIUM Verified

Collaborator meets ABMIUM quality standards and overall product performance standards have been met.

ISO
ISO 9001

Quality management certification.

RUO
Research Use Only

For research applications. Not for diagnostic use.

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