CLN5 rabbit pAb
CLN5 rabbit pAb from ELK Biotechnology Read more ›

Product Description
CLN5 rabbit pAb is an ELK Biotechnology antibody for research workflows involving CLN5.
Background
ceroid-lipofuscinosis, neuronal 5(CLN5) Homo sapiens This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.[provided by RefSeq, Oct 2008],
Additional antibody information
| Specificity | CLN5 Polyclonal Antibody detects endogenous levels of CLN5 protein. |
|---|---|
| Validation evidence captions | Western Blot analysis of 293T cells using CLN5 Polyclonal Antibody diluted at 1:1000 | Western blot analysis of CLN5 Antibody. The lane on the right is blocked with the CLN5 peptide. | Western blot analysis of the lysates from COLO205 cells using CLN5 antibody. |
Key Facts
| Target | CLN5 |
| Also known as | CLN5; Ceroid-lipofuscinosis neuronal protein 5; Protein CLN5 |
| Concentration | 1 mg/ml |
| Working concentration | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Species reactivity | Human;Mouse;Rat |
| Observed band | 48kD |
| Cellular localization | Ceroid-lipofuscinosis neuronal protein 5, secreted form: Lysosome .; Ceroid-lipofuscinosis neuronal protein 5: Membrane ; Single-pass type II membrane protein . An amphipathic anchor region facilitates its association with the membrane. . |
| Purity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Form / buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Research area | >>Lysosome |
| Host species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Tested applications |
WBELISA |
| Dilution range | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CLN5. AA range:171-220 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Reactivity & Application Validation
3 speciess| Species | WB | IHC | IF | ELISA | IP | FCM | CHIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Mouse | |||||||
| Rat |
| Species | Dilution | Notes |
|---|---|---|
| Human | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. | — |
| Mouse | — | — |
| Rat | — | — |
| Species | Dilution | Notes |
|---|
Specifications
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Not intended for diagnostic or therapeutic use.