Primary Antibody ISO 9001|ABMIUM Verified™
ABM98391

CLN5 rabbit pAb

ISO 9001|ABMIUM Verified™|Antibody

CLN5 rabbit pAb from ELK Biotechnology Read more ›

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CLN5 rabbit pAb
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CLN5 rabbit pAb

Product Description

CLN5 rabbit pAb is an ELK Biotechnology antibody for research workflows involving CLN5.

Background

ceroid-lipofuscinosis, neuronal 5(CLN5) Homo sapiens This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.[provided by RefSeq, Oct 2008],

Additional antibody information

Specificity CLN5 Polyclonal Antibody detects endogenous levels of CLN5 protein.
Validation evidence captions Western Blot analysis of 293T cells using CLN5 Polyclonal Antibody diluted at 1:1000 | Western blot analysis of CLN5 Antibody. The lane on the right is blocked with the CLN5 peptide. | Western blot analysis of the lysates from COLO205 cells using CLN5 antibody.

Key Facts

Product type Primary Antibody Target: CLN5
Target CLN5
Also known as CLN5; Ceroid-lipofuscinosis neuronal protein 5; Protein CLN5
Concentration 1 mg/ml
Working concentration Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Species reactivity Human;Mouse;Rat
Observed band 48kD
Cellular localization Ceroid-lipofuscinosis neuronal protein 5, secreted form: Lysosome .; Ceroid-lipofuscinosis neuronal protein 5: Membrane ; Single-pass type II membrane protein . An amphipathic anchor region facilitates its association with the membrane. .
Purity The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form / buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Research area >>Lysosome
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Conjugation Unconjugated
Tested applications
WBELISA
Dilution range Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human CLN5. AA range:171-220
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reactivity & Application Validation

3 speciess
ABMIUM Validated™ ABMIUM Verified™ Expected Performance Not suitable
SpeciesWBIHCIFELISAIPFCMCHIP
Human
Mouse
Rat
ABMIUM Validated™ WB
Species Dilution Notes
Human Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Mouse
Rat
ABMIUM Validated™ ELISA
Species Dilution Notes

Specifications

Target
CLN5
Also known as
CLN5; Ceroid-lipofuscinosis neuronal protein 5; Protein CLN5
Concentration
1 mg/ml
Working concentration
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form / buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Species reactivity
Human;Mouse;Rat
Tested applications
WBELISA
Immunogen
The antiserum was produced against synthesized peptide derived from human CLN5. AA range:171-220
Observed band
48kD
Cellular localization
Ceroid-lipofuscinosis neuronal protein 5, secreted form: Lysosome .; Ceroid-lipofuscinosis neuronal protein 5: Membrane ; Single-pass type II membrane protein . An amphipathic anchor region facilitates its association with the membrane. .
Dilution range
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage & Stability

Long-term storage
-20°C/1 year
Storage conditions
-20°C/1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Compliance & Certifications

ISO 9001
ISO 9001:2015 Certified

Manufactured under ISO 9001:2015 quality management standards.

RUO
For Research Use Only

Not intended for diagnostic or therapeutic use.

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