CD36 rabbit pAb from ELK Biotechnology Read more ›
CD36 rabbit pAb is a research-use antibody from ELK Biotechnology for studying CD36 in WB, IHC, ELISA workflows with listed reactivity for Human, Mouse, Rat, Tilapia. Specifications and supporting documents below should be reviewed when planning the experiment.
The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014],
| Specificity | CD36 Polyclonal Antibody detects endogenous levels of CD36 protein. |
|---|---|
| Validation evidence captions | Western Blot analysis of MCF7, 4T1 cells using CD36 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000 | Immunohistochemical analysis of paraffin-embedded human Tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min). |
| Collaborator | ELK Biotechnology |
| Partner model | ES4315 |
| Target | CD36 |
| Research areas | >>PPAR signaling pathway, >>Phagosome, >>AMPK signaling pathway, >>ECM-receptor interaction, >>Hematopoietic cell lineage, >>Adipocytokine signaling pathway, >>Insulin resistance, >>Fat digestion and absorption, >>Cholesterol metabolism, >>Malaria, >>Diabetic cardiomyopathy, >>Lipid and atherosclerosis |
| Reactivity | Human,Mouse,Rat,Tilapia |
| Applications | WB,IHC,ELISA |
| Conjugation | Unconjugated |
| Dilution range | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human CD36. AA range:331-380 |
| Concentration | 1 mg/ml |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Assay type | Antibody validation/application |
| Expression system | Adipocyte,Liver,Mammary gland,Milk,Placenta,Platelet,Skeletal muscle, |
| Purity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Mouse | |||||||
| Rat | |||||||
| Tilapia |
| Species | Dilution | Notes |
|---|---|---|
| Human | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. | — |
| Mouse | — | — |
| Rat | — | — |
| Tilapia | — | — |
| Species | Dilution | Notes |
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| Species | Dilution | Notes |
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Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
Quality management certification.
For research applications. Not for diagnostic use.
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