GABAA Rα6 rabbit pAb from ELK Biotechnology Read more ›
GABAA Rα6 rabbit pAb is a research-use antibody from ELK Biotechnology for studying GABAA Rα6 in WB, ELISA workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008],
| Specificity | GABAA Rα6 Polyclonal Antibody detects endogenous levels of GABAA Rα6 protein. |
|---|---|
| Validation evidence captions | Western Blot analysis of various cells using GABAA Rα6 Polyclonal Antibody diluted at 1:500 | Western Blot analysis of MOUSE-BRAIN cells using GABAA Rα6 Polyclonal Antibody diluted at 1:500 | Western blot analysis of lysates from HeLa and Jurkat cells, using GABRA6 Antibody. The lane on the right is blocked with the synthesized peptide. |
| Collaborator | ELK Biotechnology |
| Partner model | ES2388 |
| Target | GABAA Rα6 |
| Research areas | >>Neuroactive ligand-receptor interaction, >>Retrograde endocannabinoid signaling, >>GABAergic synapse, >>Taste transduction, >>Morphine addiction, >>Nicotine addiction |
| Reactivity | Human,Mouse,Rat |
| Applications | WB,ELISA |
| Conjugation | Unconjugated |
| Dilution range | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GABRA6. AA range:61-110 |
| Concentration | 1 mg/ml |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Assay type | Antibody validation/application |
| Expression system | Cerebellum, |
| Purity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Mouse | |||||||
| Rat |
| Species | Dilution | Notes |
|---|---|---|
| Human | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. | — |
| Mouse | — | — |
| Rat | — | — |
| Species | Dilution | Notes |
|---|
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
Quality management certification.
For research applications. Not for diagnostic use.
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