ABM97081
Desmin Rabbit pAb
ISO 9001|ABMIUM Verified™|Antibody
Desmin Rabbit pAb from ELK Biotechnology Read more ›
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Product Description
Desmin Rabbit pAb is an ELK Biotechnology antibody for research workflows involving Desmin.
Background
This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq, Jul 2008],
Additional antibody information
| Specificity | This antibody detects endogenous levels of Desmin at Human, Mouse,Rat |
|---|---|
| Validation evidence captions | Western blot analysis of 1)Mouse Heart Tissue, 2) Rat Heart Tissue Lysate using DesminRabbit Polyclonal Antibody diluted at 1:2,000. | Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min). |
Key Facts
Product type
Primary Antibody›
Target: Desmin
| Target | Desmin |
| Also known as | Desmin |
| Concentration | 1 mg/ml |
| Working concentration | IHC-p1:50-200 ,WB 1:1000-2000 |
| Species reactivity | Human; Mouse;Rat |
| Observed band | 54kD |
| Cellular localization | Cytoplasmic |
| Purity | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Form / buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.75% sodium azide. |
| Research area | >>Hypertrophic cardiomyopathy;>>Arrhythmogenic right ventricular cardiomyopathy;>>Dilated cardiomyopathy |
| Host species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Tested applications |
WBIHC |
| Dilution range | IHC-p1:50-200 ,WB 1:1000-2000 |
| Immunogen | Synthesized peptide derived from human Desmin AA range: 197-247 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
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Reactivity & Application Validation
3 speciess| Species | WB | IHC | IF | ELISA | IP | FCM | CHIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Mouse | |||||||
| Rat |
ABMIUM Validated™
WB
| Species | Dilution | Notes |
|---|---|---|
| Human | IHC-p1:50-200 | — |
| Mouse | — | — |
| Rat | — | — |
ABMIUM Validated™
IHC
| Species | Dilution | Notes |
|---|
Specifications
Target
Desmin
Also known as
Desmin
Concentration
1 mg/ml
Working concentration
IHC-p1:50-200 ,WB 1:1000-2000
Purity
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Form / buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.75% sodium azide.
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Species reactivity
Human; Mouse;Rat
Tested applications
WBIHC
Immunogen
Synthesized peptide derived from human Desmin AA range: 197-247
Observed band
54kD
Cellular localization
Cytoplasmic
Dilution range
IHC-p1:50-200 ,WB 1:1000-2000
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Storage & Stability
Long-term storage
-20°C/1 year
Storage conditions
-20°C/1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.75% sodium azide.
Compliance & Certifications
ISO 9001
ISO 9001:2015 Certified
Manufactured under ISO 9001:2015 quality management standards.
RUO
For Research Use Only
Not intended for diagnostic or therapeutic use.
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