PEPC rabbit pAb
PEPC rabbit pAb from ELK Biotechnology Read more ›
Product Description
PEPC rabbit pAb is an ELK Biotechnology antibody for research workflows involving PEPC.
Background
This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009],
Additional antibody information
| Specificity | The antibody detects endogenous PEPC protein. |
|---|---|
| Validation evidence captions | Western blot analysis of Maize, diluted at 1:4000. Secondary antibody(catalog#:RS0002) was diluted at 1:20000 |
Key Facts
| Target | PEPC |
| Also known as | PGC; Gastricsin; Pepsinogen C |
| Working concentration | WB: 1:2000-5000 |
| Species reactivity | Plants |
| Observed band | 105-109kD |
| Cellular localization | extracellular space,extracellular exosome, |
| Purity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Form / buffer | PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol. |
| Research area | Antibody Research |
| Host species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Tested applications |
WB |
| Dilution range | WB: 1:2000-5000 |
| Immunogen | Synthetic Peptide of PEPC |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Reactivity & Application Validation
1 species| Species | WB | IHC | IF | ELISA | IP | FCM | CHIP |
|---|---|---|---|---|---|---|---|
| Plants |
| Species | Dilution | Notes |
|---|---|---|
| Plants | WB: 1:2000-5000 | — |
Specifications
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Not intended for diagnostic or therapeutic use.