BEAN1 rabbit pAb
BEAN1 rabbit pAb from ELK Biotechnology Read more ›
Product Description
BEAN1 rabbit pAb is an ELK Biotechnology antibody for research workflows involving BEAN1.
Background
The protein encoded by this gene is one of several proteins that interact with NEDD4, a member of a family of ubiquitin-protein ligases. These proteins have PY motifs in common that bind to the WW domains of NEDD4. NEDD4 is developmentally regulated, and is highly expressed in embryonic tissues. Mutations in this gene (i.e., intronic insertions of >100 copies of pentanucleotide repeats including a (TGGAA)n sequence) are associated with spinocerebellar ataxia type 31. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010],
Additional antibody information
| Specificity | This antibody detects endogenous levels of BEAN1 at Human/Mouse |
|---|---|
| Validation evidence captions | Western blot analysis of lysates from 3T3 cells, primary antibody was diluted at 1:1000, 4°over night |
Key Facts
| Target | BEAN1 |
| Concentration | 1 mg/ml |
| Working concentration | wb 1:1000 IP:1:50-200 |
| Species reactivity | Human; Mouse |
| Cellular localization | Membrane ; Single-pass membrane protein . |
| Purity | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Form / buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Research area | >>Spinocerebellar ataxia |
| Host species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Tested applications |
WB |
| Dilution range | wb 1:1000 IP:1:50-200 |
| Immunogen | Synthesized peptide derived from human BEAN1 AA range: 146-196 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
Reactivity & Application Validation
2 speciess| Species | WB | IHC | IF | ELISA | IP | FCM | CHIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Mouse |
| Species | Dilution | Notes |
|---|---|---|
| Human | wb 1:1000 IP:1:50-200 | — |
| Mouse | — | — |
Specifications
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Not intended for diagnostic or therapeutic use.