CCL17 rabbit pAb
CCL17 rabbit pAb from ELK Biotechnology Read more ›
Product Description
CCL17 rabbit pAb is an ELK Biotechnology antibody for research workflows involving CCL17.
Background
This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq, Sep 2014],
Additional antibody information
| Specificity | This antibody detects endogenous levels of human CCL17 |
|---|---|
| Validation evidence captions | Western blot analysis of various lysates, primary antibody was diluted at 1:1000, 4° over night, secondary antibody(cat: RS23920)was diluted at 1:10000, 37° 1hour. |
Key Facts
| Target | CCL17 |
| Also known as | C-C motif chemokine 17 (CC chemokine TARC;Small-inducible cytokine A17;Thymus and activation-regulated chemokine) |
| Concentration | 1 mg/ml |
| Working concentration | WB 1:500-2000, ELISA(peptide)1:5000-20000 |
| Species reactivity | Human;Rat;Mouse; |
| Observed band | 10kD |
| Cellular localization | Secreted. |
| Purity | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Form / buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Research area | >>Cytokine-cytokine receptor interaction;>>Viral protein interaction with cytokine and cytokine receptor;>>Chemokine signaling pathway;>>C-type lectin receptor signaling pathway;>>IL-17 signaling pathway |
| Host species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Tested applications |
WBELISA |
| Dilution range | WB 1:500-2000, ELISA(peptide)1:5000-20000 |
| Immunogen | Synthesized peptide derived from human CCL17 AA range: 21-70 |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Reactivity & Application Validation
3 speciess| Species | WB | IHC | IF | ELISA | IP | FCM | CHIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Rat | |||||||
| Mouse |
| Species | Dilution | Notes |
|---|---|---|
| Human | WB 1:500-2000 | — |
| Rat | — | — |
| Mouse | — | — |
| Species | Dilution | Notes |
|---|
Specifications
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Not intended for diagnostic or therapeutic use.