Primary Antibody ISO 9001|ABMIUM Verified™
ABM95778

GNG12 Rabbit pAb

ISO 9001|ABMIUM Verified™|Antibody

GNG12 Rabbit pAb from ELK Biotechnology Read more ›

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GNG12 Rabbit pAb
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GNG12 Rabbit pAb

Product Description

GNG12 Rabbit pAb is an ELK Biotechnology antibody for research workflows involving GNG12.

Background

function:Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.,similarity:Belongs to the G protein gamma family.,subunit:G proteins are composed of 3 units, alpha, beta and gamma.,

Additional antibody information

Specificity This antibody detects endogenous levels of human GNG12
Validation evidence captions Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).

Key Facts

Product type Primary Antibody Target: GNG12
Target GNG12
Also known as Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
Concentration 1 mg/ml
Working concentration IHC-p 1:50-200, ELISA(peptide)1:5000-20000
Species reactivity Human; Mouse
Cellular localization Cell membrane ; Lipid-anchor ; Cytoplasmic side .
Purity The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Form / buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Research area >>MAPK signaling pathway;>>Ras signaling pathway;>>Chemokine signaling pathway;>>PI3K-Akt signaling pathway;>>Apelin signaling pathway;>>Circadian entrainment;>>Retrograde endocannabinoid signaling;>>Glutamatergic synapse;>>Cholinergic synapse;>>Serotonergic synapse;>>GABAergic synapse;>>Dopaminergic synapse;>>Regulation of actin cytoskeleton;>>Relaxin signaling pathway;>>Morphine addiction;>>Alcoholism;>>Human cytomegalovirus infection;>>Kaposi sarcoma-associated herpesvirus infection;>>Human immunodeficiency virus 1 infection;>>Pathways in cancer
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Conjugation Unconjugated
Tested applications
IHCELISA
Dilution range IHC-p 1:50-200, ELISA(peptide)1:5000-20000
Immunogen Synthesized peptide derived from human GNG12 AA range: 1-50
Purification The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
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Reactivity & Application Validation

2 speciess
ABMIUM Validated™ ABMIUM Verified™ Expected Performance Not suitable
SpeciesWBIHCIFELISAIPFCMCHIP
Human
Mouse
ABMIUM Validated™ IHC
Species Dilution Notes
Human IHC-p 1:50-200
Mouse
ABMIUM Validated™ ELISA
Species Dilution Notes

Specifications

Target
GNG12
Also known as
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
Concentration
1 mg/ml
Working concentration
IHC-p 1:50-200, ELISA(peptide)1:5000-20000
Purity
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Form / buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Species reactivity
Human; Mouse
Tested applications
IHCELISA
Immunogen
Synthesized peptide derived from human GNG12 AA range: 1-50
Cellular localization
Cell membrane ; Lipid-anchor ; Cytoplasmic side .
Dilution range
IHC-p 1:50-200, ELISA(peptide)1:5000-20000
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Storage & Stability

Long-term storage
-20°C/1 year
Storage conditions
-20°C/1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Compliance & Certifications

ISO 9001
ISO 9001:2015 Certified

Manufactured under ISO 9001:2015 quality management standards.

RUO
For Research Use Only

Not intended for diagnostic or therapeutic use.

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