Primary Antibody ISO 9001|ABMIUM Verified™
ABM94479

SMOX rabbit pAb

ISO 9001|ABMIUM Verified™|Antibody

SMOX rabbit pAb from ELK Biotechnology Read more ›

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SMOX rabbit pAb
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SMOX rabbit pAb

Product Description

SMOX rabbit pAb is an ELK Biotechnology antibody for research workflows involving SMOX.

Background

Polyamines are ubiquitous polycationic alkylamines which include spermine, spermidine, putrescine, and agmatine. These molecules participate in a broad range of cellular functions which include cell cycle modulation, scavenging reactive oxygen species, and the control of gene expression. These molecules also play important roles in neurotransmission through their regulation of cell-surface receptor activity, involvement in intracellular signalling pathways, and their putative roles as neurotransmitters. This gene encodes an FAD-containing enzyme that catalyzes the oxidation of spermine to spermadine and secondarily produces hydrogen peroxide. Multiple transcript variants encoding different isoenzymes have been identified for this gene, some of which have failed to demonstrate significant oxidase activity on natural polyamine substrates. The characterized isoenzymes have distinctive biochemical characteristics and substrate specificities, suggesting the existence of additional levels of complexity in polyamine catabolism. [provided by RefSeq, Jul 2012],

Additional antibody information

Specificity This antibody detects endogenous levels of SMOX at Human/Mouse
Validation evidence captions Western blot analysis of lysates from 3T3 cells, primary antibody was diluted at 1:1000, 4°over night

Key Facts

Product type Primary Antibody Target: SMOX
Target SMOX
Concentration 1 mg/ml
Working concentration WB 1:500-2000
Species reactivity Human; Mouse
Cellular localization Isoform 1: Cytoplasm. Nucleus.; Isoform 4: Cytoplasm. Nucleus.; Isoform 6: Cytoplasm. Nucleus.
Purity The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Form / buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Research area >>Arginine and proline metabolism;>>beta-Alanine metabolism;>>Metabolic pathways
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Conjugation Unconjugated
Tested applications
WB
Dilution range WB 1:500-2000
Immunogen Synthesized peptide derived from human SMOX AA range: 212-262
Purification The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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Reactivity & Application Validation

2 speciess
ABMIUM Validated™ ABMIUM Verified™ Expected Performance Not suitable
SpeciesWBIHCIFELISAIPFCMCHIP
Human
Mouse
ABMIUM Validated™ WB
Species Dilution Notes
Human WB 1:500-2000
Mouse

Specifications

Target
SMOX
Concentration
1 mg/ml
Working concentration
WB 1:500-2000
Purity
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Form / buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Species reactivity
Human; Mouse
Tested applications
WB
Immunogen
Synthesized peptide derived from human SMOX AA range: 212-262
Cellular localization
Isoform 1: Cytoplasm. Nucleus.; Isoform 4: Cytoplasm. Nucleus.; Isoform 6: Cytoplasm. Nucleus.
Dilution range
WB 1:500-2000
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Storage & Stability

Long-term storage
-20°C/1 year
Storage conditions
-20°C/1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Compliance & Certifications

ISO 9001
ISO 9001:2015 Certified

Manufactured under ISO 9001:2015 quality management standards.

RUO
For Research Use Only

Not intended for diagnostic or therapeutic use.

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