HSP 90 (Acetyl Lys435) rabbit pAb from ELK Biotechnology Read more ›
HSP 90 (Acetyl Lys435) rabbit pAb is a research-use antibody from ELK Biotechnology for studying HSP 90 in WB, ELISA workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.
The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],
| Specificity | Acetyl-HSP 90 (K435) Polyclonal Antibody detects endogenous levels of HSP 90 protein only when acetylated at K435. |
|---|---|
| Validation evidence captions | Western Blot analysis of A549 cells using Acetyl-HSP 90 (K435) Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000 | Western Blot analysis of A549 cells using Acetyl-HSP 90 (K435) Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000 |
| Collaborator | ELK Biotechnology |
| Partner model | ES1105 |
| Target | HSP 90 |
| Research areas | >>Protein processing in endoplasmic reticulum, >>PI3K-Akt signaling pathway, >>Necroptosis, >>Antigen processing and presentation, >>NOD-like receptor signaling pathway, >>IL-17 signaling pathway, >>Th17 cell differentiation, >>Progesterone-mediated oocyte maturation, >>Estrogen signaling pathway, >>Salmonella infection, >>Pathways in cancer, >>Chemical carcinogenesis - receptor activation, >>Prostate cancer, >>Lipid and atherosclerosis, >>Fluid shear stress and atherosclerosis |
| Reactivity | Human,Mouse,Rat |
| Applications | WB,ELISA |
| Conjugation | Unconjugated |
| Dilution range | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Synthesized acetyl-peptide derived from the human HSP 90 around the acetylation site of K435. |
| Concentration | 1 mg/ml |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Assay type | Antibody validation/application |
| Expression system | Adult brain,Brain,Brain cortex,Breast,Cajal-Retzius |
| Purity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Mouse | |||||||
| Rat |
| Species | Dilution | Notes |
|---|---|---|
| Human | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. | — |
| Mouse | — | — |
| Rat | — | — |
| Species | Dilution | Notes |
|---|
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
Quality management certification.
For research applications. Not for diagnostic use.
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