Primary Antibody ISO 9001|ABMIUM Verified™
ABM93027

Cleaved-Plasminogen HC A short form (V98) rabbit pAb

ISO 9001|ABMIUM Verified™|Antibody

Cleaved-Plasminogen HC A short form (V98) rabbit pAb from ELK Biotechnology Read more ›

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Cleaved-Plasminogen HC A short form (V98) rabbit pAb
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Cleaved-Plasminogen HC A short form (V98) rabbit pAb

Product Description

Cleaved-Plasminogen HC A short form (V98) rabbit pAb is an ELK Biotechnology antibody for research workflows involving Plasminogen HC A.

Background

The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009],

Additional antibody information

Specificity Cleaved-Plasminogen HC A short form (V98) Polyclonal Antibody detects endogenous levels of fragment of activated Plasminogen HC A short form protein resulting from cleavage adjacent to V98.
Validation evidence captions Western Blot analysis of various cells using Cleaved-Plasminogen HC A short form (V98) Polyclonal Antibody | Western blot analysis of PLMN (heavy chain A short form, Cleaved-Val98) Antibody. The lane on the right is blocked with the PLMN (heavy chain A short form, Cleaved-Val98) peptide.

Key Facts

Product type Primary Antibody Target: Plasminogen HC A
Target Plasminogen HC A
Also known as PLG; Plasminogen
Concentration 1 mg/ml
Working concentration Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Species reactivity Human;Mouse;Rat
Observed band 54kD
Cellular localization Secreted . Locates to the cell surface where it is proteolytically cleaved to produce the active plasmin. Interaction with HRG tethers it to the cell surface.
Purity The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form / buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Research area >>Neuroactive ligand-receptor interaction;>>Complement and coagulation cascades;>>Staphylococcus aureus infection;>>Influenza A
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Conjugation Unconjugated
Tested applications
WBELISA
Dilution range Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human PLMN. AA range:79-128
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reactivity & Application Validation

3 speciess
ABMIUM Validated™ ABMIUM Verified™ Expected Performance Not suitable
SpeciesWBIHCIFELISAIPFCMCHIP
Human
Mouse
Rat
ABMIUM Validated™ WB
Species Dilution Notes
Human Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Mouse
Rat
ABMIUM Validated™ ELISA
Species Dilution Notes

Specifications

Target
Plasminogen HC A
Also known as
PLG; Plasminogen
Concentration
1 mg/ml
Working concentration
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form / buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Species reactivity
Human;Mouse;Rat
Tested applications
WBELISA
Immunogen
The antiserum was produced against synthesized peptide derived from human PLMN. AA range:79-128
Observed band
54kD
Cellular localization
Secreted . Locates to the cell surface where it is proteolytically cleaved to produce the active plasmin. Interaction with HRG tethers it to the cell surface.
Dilution range
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage & Stability

Long-term storage
-20°C/1 year
Storage conditions
-20°C/1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Compliance & Certifications

ISO 9001
ISO 9001:2015 Certified

Manufactured under ISO 9001:2015 quality management standards.

RUO
For Research Use Only

Not intended for diagnostic or therapeutic use.

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