Cleaved-MPO 89k (A49) rabbit pAb from ELK Biotechnology Read more ›
Cleaved-MPO 89k (A49) rabbit pAb is a research-use antibody from ELK Biotechnology for studying MPO in WB, ELISA workflows with listed reactivity for Human, Rat, Mouse. Specifications and supporting documents below should be reviewed when planning the experiment.
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014],
| Specificity | Cleaved-MPO 89k (A49) Polyclonal Antibody detects endogenous levels of fragment of activated MPO 89k protein resulting from cleavage adjacent to A49. |
|---|---|
| Validation evidence captions | Western Blot analysis of various cells using Cleaved-MPO 89k (A49) Polyclonal Antibody |
| Collaborator | ELK Biotechnology |
| Partner model | ES1070 |
| Target | MPO |
| Research areas | >>Drug metabolism - other enzymes, >>Phagosome, >>Neutrophil extracellular trap formation, >>Transcriptional misregulation in cancer, >>Acute myeloid leukemia |
| Reactivity | Human,Rat,Mouse |
| Applications | WB,ELISA |
| Conjugation | Unconjugated |
| Dilution range | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Synthesized peptide derived from Cleaved-MPO 89k (A49) . at AA range: 40-120 |
| Concentration | 1 mg/ml |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Assay type | Antibody validation/application |
| Expression system | Leukemia,Leukocyte,Liver,Plasma,Saliva, |
| Purity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Rat | |||||||
| Mouse |
| Species | Dilution | Notes |
|---|---|---|
| Human | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. | — |
| Rat | — | — |
| Mouse | — | — |
| Species | Dilution | Notes |
|---|
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
Quality management certification.
For research applications. Not for diagnostic use.
No customer reviews yet.
