Biotinylated Human CD3E (C-Fc-Avi)
Biotinylated Human CD3E (C-Fc-Avi) from ELK Biotechnology Read more ›
Product Description
Biotinylated Human CD3E (C-Fc-Avi) is an ELK Biotechnology recombinant protein for research use.
Description
Biotinylated Recombinant Human T-cell Surface Glycoprotein CD3 Epsilon Chain is produced by our Mammalian expression system and the target gene encoding Asp23-Asp126 is expressed with a Fc, Avi tag at the C-terminus.
Background
T-Cell Surface Glycoprotein CD3 ε Chain (CD3ε) is a single-pass type I membrane protein. CD3ε contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3ε is a polypeptide encoded by the CD3E gene on chromosome 11 in humans. The T cell receptor-CD3 complex (TCR/CD3 complex) is involved in T-cell development and several intracellular signal-transduction pathways. This complex is critical for T-cell development and function, and represents one of the most complex transmembrane receptors. The T cell receptor-CD3 complex is unique in having ten cytoplasmic immunoreceptor tyrosine-based activation motifs (ITAMs). TCR/CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
Handling information
| Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100µg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
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| Delivery condition | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Key Facts
| Target | Biotinylated Human CD3E |
| Also known as | T-Cell Surface Glycoprotein CD3 Epsilon Chain; T-Cell Surface Antigen T3/Leu-4 Epsilon Chain; CD3e; CD3E; T3E |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
| Form / buffer | Lyophilized protein |
| Research area | Molecular Biology |
| Specification | PURITY | ENDOTOXIN | BIOACTIVITY |
|---|---|---|---|
| Product QC |
Specifications
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Not intended for diagnostic or therapeutic use.