Collaborator ELK Biotechnology
Recombinant ProteinsISO 9001:2015
ABM100989

Recombinant Human Serpin B6 (N-Trx-6His)

ISO 9001|ABMIUM Verified™|Protein

Recombinant Human Serpin B6 (N-Trx-6His) from ELK Biotechnology Read more ›

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Product Description

Recombinant Human Serpin B6 (N-Trx-6His) is a research-use recombinant protein from ELK Biotechnology preparation representing Serpin B6 supplied as Lyophilized. Review the expression, purity, formulation and storage specifications below before selecting it for an assay or functional workflow.

Description

Recombinant Human Serine Protease Inhibitor-clade B6 is produced by our E.coli expression system and the target gene encoding Met1-Pro376 is expressed with a Trx, 6His tag at the N-terminus.

Background

Serpin B6 belongs to the serpin family. Serpin B6 localizes to the cytoplasm. Serpin B6 is expressed in many tissues, abundantly by mast cells in different tissues and mastocytoma lesions. Serpin B6 may be involved in the regulation of serine proteinases present in the brain or extravasated from the blood. In addition, Serpin B6 may play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss.

Handling information

Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100µg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Delivery condition The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

Key Facts

Product typeRecombinant Proteins Target: Serpin B6
Collaborator ELK Biotechnology
Partner model EPT265
Target Serpin B6
Research areasMolecular Biology
Reactivity Product QC:C
Applications Protein research
Assay type Recombinant protein
Purity >90% by SDS-PAGE
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
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Validation Matrix

1 category
ABMIUM Validated™ ABMIUM Verified™ Expected Performance Not suitable
CategoryPurityEndotoxinBioactivity
Product QC

Specifications

Target
Serpin B6
Also known as
Serpin B6; Cytoplasmic Antiproteinase; CAP; Peptidase Inhibitor 6; PI-6; Placental Thrombin Inhibitor; SERPINB6; PI6; PTI
Purity
>90% by SDS-PAGE
Form / buffer
Lyophilized

Storage & Stability

Long-term storage
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Compliance & Certifications

ABMIUM
ABMIUM Verified

Collaborator meets ABMIUM quality standards and overall product performance standards have been met.

ISO
ISO 9001

Quality management certification.

RUO
Research Use Only

For research applications. Not for diagnostic use.

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