Home » Recombinant Mouse B7-H4 (C-Fc)
Recombinant Protein ISO 9001|ABMIUM Verified™
ABM100928

Recombinant Mouse B7-H4 (C-Fc)

ISO 9001|ABMIUM Verified™|Protein

Recombinant Mouse B7-H4 (C-Fc) from ELK Biotechnology Read more ›

Related formats
No image available

Product Description

Recombinant Mouse B7-H4 (C-Fc) is an ELK Biotechnology recombinant protein for research use.

Description

Recombinant Mouse B7 Homolog 4 is produced by our Mammalian expression system and the target gene encoding Phe29-Pro258 is expressed with a Fc tag at the C-terminus.

Background

Mouse V-set domain-containing T-cell activation inhibitor 1/VTCN1/B7-H4 is glycosylated member of the B7 family of immune co‑stimulatory proteins. B7-H4 consists of extracellular domain (ECD) with one Ig-like V-set domain and one Ig-like C2-set domain. It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. It also involved in promoting epithelial cell transformation.

Handling information

Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100µg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Delivery condition The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

Key Facts

Product type Recombinant Protein› Target: B7-H4
Target B7-H4
Also known as V-set domain containing T-cell activation inhibitor 1; B7 homolog 4; Protein B7S1; B7-H4; VTCN1
Purity Greater than 95% as determined by reducing SDS-PAGE.
Form / buffer Lyophilized protein
Research area Molecular Biology
Why researchers trust ABMIUM
2,000+ Researchers trust us
50,000+ Citations
ISO 9001 Certified Collaborators

1 specification
ABMIUM Validated™ ABMIUM Verified™ Expected Performance Not suitable
SpecificationPURITYENDOTOXINBIOACTIVITY
Product QC

Specifications

Target
B7-H4
Also known as
V-set domain containing T-cell activation inhibitor 1; B7 homolog 4; Protein B7S1; B7-H4; VTCN1
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Form / buffer
Lyophilized protein

Storage & Stability

Long-term storage
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Storage conditions
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Compliance & Certifications

ISO 9001
ISO 9001:2015 Certified

Manufactured under ISO 9001:2015 quality management standards.

RUO
For Research Use Only

Not intended for diagnostic or therapeutic use.

Customer Reviews

Recently Viewed