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Recombinant Protein ISO 9001|ABMIUM Verified™
ABM100916

Recombinant Human NRG1Beta (71AA)

ISO 9001|ABMIUM Verified™|Protein

Recombinant Human NRG1Beta (71AA) from ELK Biotechnology Read more ›

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Product Description

Recombinant Human NRG1Beta (71AA) is an ELK Biotechnology recombinant protein for research use.

Description

Recombinant Human Neuregulin-1 Beta is produced by our E.coli expression system and the target gene encoding Thr176-Lys246 is expressed.

Background

neuregulin-1 (heregulin-1，NRG1) is a member of neuregulin family, which is comprised of four genes that encode a large number of secreted or membrane-bound isoforms. All family members share an EGF-like domain that interacts with the ErbB family of tyrosine kinase receptors. NRG1 isoforms can be classified into type I, type II and type III isoforms. NRG1 directs ligand for ERBB3 and ERBB4 tyrosine kinase receptors, concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. NRG proteins show distinct spatial and temporal expression patterns and play important roles during development of both the nervous system and the heart.

Handling information

Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100µg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Delivery condition The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

Key Facts

Product type Recombinant Protein› Target: NRG1Beta
Target NRG1Beta
Also known as Pro-neuregulin-1; Neuregulin-1 beta 1; NRG1-beta 1; HRG1-beta 1; EGF;NRG1; GGF; HGL; HRGA; NDF; SMDF
Purity Greater than 95% as determined by reducing SDS-PAGE.
Form / buffer Lyophilized protein
Research area Molecular Biology
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1 specification
ABMIUM Validated™ ABMIUM Verified™ Expected Performance Not suitable
SpecificationPURITYENDOTOXINBIOACTIVITY
Product QC

Specifications

Target
NRG1Beta
Also known as
Pro-neuregulin-1; Neuregulin-1 beta 1; NRG1-beta 1; HRG1-beta 1; EGF;NRG1; GGF; HGL; HRGA; NDF; SMDF
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Form / buffer
Lyophilized protein

Storage & Stability

Long-term storage
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Storage conditions
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Compliance & Certifications

ISO 9001
ISO 9001:2015 Certified

Manufactured under ISO 9001:2015 quality management standards.

RUO
For Research Use Only

Not intended for diagnostic or therapeutic use.

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