Recombinant Human Sting (N-Sumo-6His)
Recombinant Human Sting (N-Sumo-6His) from ELK Biotechnology Read more ›
Product Description
Recombinant Human Sting (N-Sumo-6His) is an ELK Biotechnology recombinant protein for research use.
Description
Recombinant Human Stimulator of Interferon Genes Protein is produced by our E.coli expression system and the target gene encoding Val155-Val341 is expressed with a 6His, Sumo tag at the N-terminus.
Background
Stimulator of Interferon Gene(Sting,TMEM173) belongs to the TMEM173 family. STING is 379 amino acids (aa) in length. It contains an N-terminal cytoplasmic region (aa 1-20), four transmembrane segments (aa 21-173), and a C-terminal cytoplasmic domain (aa 174-379). It ubiquitously expressed in skin endothelial cells, alveolar type 2 pneumocytes, bronchial epithelium and alveolar macrophagesand. Its subunit structure associated with the MHC-II complex and Interacts with DDX58/RIG-I, MAVS and SSR2, RNF5 and TRIM56 along with TBK1. This type of protein often uses as facilitator of innate immune signaling that acts as a sensor of cytosolic DNA from bacteria and viruses and promotes the production of type I interferon.
Handling information
| Delivery condition | The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below. |
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Key Facts
| Target | Sting |
| Also known as | Stimulator of interferon genes protein;TMEM173;Mediator of IRF3 activation;sting; |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
| Form / buffer | Lyophilized protein |
| Research area | Molecular Biology |
| Specification | PURITY | ENDOTOXIN | BIOACTIVITY |
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| Product QC |
Specifications
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Not intended for diagnostic or therapeutic use.