Recombinant Human Asprosin (N-8His)
Recombinant Human Asprosin (N-8His) from ELK Biotechnology Read more ›
Product Description
Recombinant Human Asprosin (N-8His) is an ELK Biotechnology recombinant protein for research use.
Description
Recombinant Human Asprosin is produced by our Mammalian expression system and the target gene encoding Ser2732-His2871 is expressed with a 8His tag at the N-terminus.
Background
Asprosin is a protein hormone that is produced by white adipose tissue in mammals (and potentially by other tissues), which is then transported to the liver and stimulates it to release glucose into the blood stream. In the liver asprosin activates rapid glucose release by a cAMP-dependent pathway. The glucose release by the liver into the blood stream is vital for brain function and survival during fasting. People with neonatal progeroid syndrome lack asprosin, while people with insulin resistance have it in abundance. In animal tests asprosin showed potential for treating type 2 diabetes. When antibodies targeting asprosin were injected into diabetic mice, blood glucose and insulin levels improved.
Handling information
| Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100µg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
|---|---|
| Delivery condition | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Key Facts
| Target | Asprosin |
| Also known as | Fibrillin-1; FBN1; Asprosin; FBN |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
| Form / buffer | Lyophilized protein |
| Research area | Molecular Biology |
| Specification | PURITY | ENDOTOXIN | BIOACTIVITY |
|---|---|---|---|
| Product QC |
Specifications
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Not intended for diagnostic or therapeutic use.