Recombinant Human TRAIL from ELK Biotechnology Read more ›
Recombinant Human TRAIL is a research-use recombinant protein from ELK Biotechnology preparation representing TRAIL supplied as Lyophilized. Review the expression, purity, formulation and storage specifications below before selecting it for an assay or functional workflow.
Recombinant Human TNF-Related Apoptosis-Inducing Ligand is produced by our E.coli expression system and the target gene encoding Arg115-Gly281 is expressed.
Human TNFSF10 is a type II transmembrane protein with an intracellular N-terminus and a ‘TNF homology domain’ (THD) at the extracellular C terminus. TNFSF10 can interact with several distinct receptors. Two of these receptors that belongs to TNFR superfamily, DR4 (TRAIL-R1) and DR5 (TRAIL-R2/TRICK2), are plasma membrane proteins containing intracellular death domains essential for activating apoptosis. TNFSF10 is promising for cancer therapy because it is cytotoxic and activates apoptosis in the majority of malignant cells, but not in normal cells.
| Delivery condition | The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below. |
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| Collaborator | ELK Biotechnology |
| Partner model | EPT141 |
| Target | TRAIL |
| Research areas | Molecular Biology |
| Reactivity | Product QC:C |
| Applications | Protein research |
| Assay type | Recombinant protein |
| Purity | >95% by SDS-PAGE |
| Endotoxin | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Category | Purity | Endotoxin | Bioactivity |
|---|---|---|---|
| Product QC |
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
Quality management certification.
For research applications. Not for diagnostic use.
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