Recombinant Rat IL-2 (C-6His)
Recombinant Rat IL-2 (C-6His) from ELK Biotechnology Read more ›
Product Description
Recombinant Rat IL-2 (C-6His) is an ELK Biotechnology recombinant protein for research use.
Description
Recombinant Rat Interleukin-2 is produced by our Mammalian expression system and the target gene encoding Ala21-Gln155 is expressed with a 6His tag at the C-terminus.
Background
Interleukin-2(IL-2)is a O-glycosylated four α-helix bundle cytokine that has potent stimulatory activity for antigenactivated T cells. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. Mature rat IL-2 shares 66% and 73% amino acid sequence identity with human and mouse IL-2,respectively. The receptor for IL-2 consists of three subunits that are present on the cell surface in varying preformed complexes. IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.
Handling information
| Delivery condition | The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below. |
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Key Facts
| Target | IL-2 |
| Also known as | Interleukin-2; IL-2; T-cell growth factor; TCGF; Aldesleukin; IL2 |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
| Form / buffer | Lyophilized protein |
| Research area | Molecular Biology |
| Specification | PURITY | ENDOTOXIN | BIOACTIVITY |
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| Product QC |
Specifications
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Not intended for diagnostic or therapeutic use.