Home » Recombinant Human CRHBP (C-6His)
Recombinant Protein ISO 9001|ABMIUM Verified™
ABM100779

Recombinant Human CRHBP (C-6His)

ISO 9001|ABMIUM Verified™|Protein

Recombinant Human CRHBP (C-6His) from ELK Biotechnology Read more ›

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Product Description

Recombinant Human CRHBP (C-6His) is an ELK Biotechnology recombinant protein for research use.

Description

Recombinant Human Corticotropin-Releasing Factor-Binding Protein is produced by our Mammalian expression system and the target gene encoding Tyr25-Leu322 is expressed with a 6His tag at the C-terminus.

Background

Corticotropin-Releasing Factor-Binding Protein (CRHBP) is a 37 kDa secreted glycoprotein that binds both CRH and urocortin in a 42 kDa extracellular complex. The molecule is approximately 300 amino acids in length and demonstrates five intrachain disulfide bonds. Difference between CRHBP from different species exist, human CRHBP is found in plasma while rodent and sheep CRHBP is limited to neuroendocrine tissues. CRHBP may inactivate CRH and may prevent inappropriate pituitary-adrenal stimulation in pregnancy. CRHBP is presumed to either sequester CRH, rendering it unavailable to cells or transport it to target tissues. Although CRF-BP concentration in the human peripheral circulation is normally low, it increases throughout pregnancy and fall back rapidly after parturition.

Handling information

Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100µg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Delivery condition The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

Key Facts

Product type Recombinant Protein› Target: CRHBP
Target CRHBP
Also known as Corticotropin-Releasing Factor-Binding Protein; CRF-BP; CRF-Binding Protein; Corticotropin-Releasing Hormone-Binding Protein; CRH-BP; CRHBP; CRFBP
Purity Greater than 95% as determined by reducing SDS-PAGE.
Form / buffer Lyophilized protein
Research area Molecular Biology
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1 specification
ABMIUM Validated™ ABMIUM Verified™ Expected Performance Not suitable
SpecificationPURITYENDOTOXINBIOACTIVITY
Product QC

Specifications

Target
CRHBP
Also known as
Corticotropin-Releasing Factor-Binding Protein; CRF-BP; CRF-Binding Protein; Corticotropin-Releasing Hormone-Binding Protein; CRH-BP; CRHBP; CRFBP
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Form / buffer
Lyophilized protein

Storage & Stability

Long-term storage
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Storage conditions
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Compliance & Certifications

ISO 9001
ISO 9001:2015 Certified

Manufactured under ISO 9001:2015 quality management standards.

RUO
For Research Use Only

Not intended for diagnostic or therapeutic use.

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