Recombinant Human/Murine/Rat BDNF
Recombinant Human/Murine/Rat BDNF from ELK Biotechnology Read more ›
Product Description
Recombinant Human/Murine/Rat BDNF is an ELK Biotechnology recombinant protein for research use.
Description
Recombinant Human Brain-Derived Neurotrophic Factor is produced by our E.coli expression system and the target gene encoding His129-Arg247 is expressed.
Background
Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and Alzheimer's disease.
Handling information
| Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100µg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
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| Delivery condition | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Key Facts
| Target | Recombinant Human/Murine/Rat BDNF |
| Also known as | Brain-Derived Neurotrophic Factor; BDNF; Abrineurin |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
| Form / buffer | Lyophilized protein |
| Research area | Molecular Biology |
| Specification | PURITY | ENDOTOXIN | BIOACTIVITY |
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| Product QC |
Specifications
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Not intended for diagnostic or therapeutic use.