Recombinant Mouse EpCAM (C-Fc)
Recombinant Mouse EpCAM (C-Fc) from ELK Biotechnology Read more ›
Product Description
Recombinant Mouse EpCAM (C-Fc) is an ELK Biotechnology recombinant protein for research use.
Description
Recombinant Mouse Epithelial Cell Adhesion Molecule is produced by our Mammalian expression system and the target gene encoding Gln24-Thr266 is expressed with a Fc tag at the C-terminus.
Background
Epithelial Cellular Adhesion Molecule (Ep-CAM), also known as EGP314, mEGP314, Protein 289A, Tumor-associated calcium signal transducer 1, CD326, belongs to the EPCAM family. Its’ monomer subunit structure interacts with phosphorylated CLDN7. Ep-CAM may act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. It plays a role in embryonic stem cells proliferation and differentiation. It also up-regulates the expression of FABP5, MYC and cyclins A and E. The post-translational modification glycosylation at Asn-198 is crucial for protein stability.
Handling information
| Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100µg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
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| Delivery condition | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Key Facts
| Target | EpCAM |
| Also known as | 17-1A; 323/A3; ACSTD1;CD326;EGP-2; EGP314; EGP40; EpCAM; MOC31; TACST-1; TACSTD1; TROP1; |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
| Form / buffer | Lyophilized protein |
| Research area | Molecular Biology |
| Specification | PURITY | ENDOTOXIN | BIOACTIVITY |
|---|---|---|---|
| Product QC |
Specifications
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Not intended for diagnostic or therapeutic use.